This proceedings volume presents the results of the 2025 Congress on Scientific and Social Innovation for Sustainability, organized by the Directorate of Research, Social Outreach, and University Extension of the Autonomous University of Santa Ana (UNASA). The document compiles multidisciplinary research across five thematic areas: Environment and Sustainability; Health, Well-being, and Quality of Life; Transformative Education; Social Development, Humanities, and Quality of Life; Transformative Education; Social Development, Humanities, and Culture; and Graphic Design. The offers a critical diagnosis of the Salvadoran reality within
these topics. Its objective is to disseminate knowledge that drives innovative and strategic solutions, strengthening the link between academia, technological
innovation, and sustainable human development.